![My first encounter with a rune. I'm guessing this isn't normally supposed to happen. : r/bindingofisaac My first encounter with a rune. I'm guessing this isn't normally supposed to happen. : r/bindingofisaac](https://external-preview.redd.it/iYAEYkl634rbo0jzCckXu4ebTfRNORjv4DGSyhPI3Hw.png?format=pjpg&auto=webp&s=75ca64e9fcb3623cba61d98657d848a989fc6366)
My first encounter with a rune. I'm guessing this isn't normally supposed to happen. : r/bindingofisaac
![Advanced Card Search - The Binding of Isaac: Four Souls: A complete reference for The Binding of Isaac: Four Souls card game. Advanced Card Search - The Binding of Isaac: Four Souls: A complete reference for The Binding of Isaac: Four Souls card game.](https://foursoulsspoiler.net/wp-content/uploads/2021/07/binding-of-isaac-four-souls-logo.png)
Advanced Card Search - The Binding of Isaac: Four Souls: A complete reference for The Binding of Isaac: Four Souls card game.
Steam Community :: Screenshot :: Playing with jera (rune that doubles all items) and blank card (can use rune or card once every four rooms) in Binding of Isaac!
![Blank Rune vanishes! Welcome to ROUND 6 of Best Runes&Souls Poll game! (Poll in comments) : r/bindingofisaac Blank Rune vanishes! Welcome to ROUND 6 of Best Runes&Souls Poll game! (Poll in comments) : r/bindingofisaac](https://preview.redd.it/blank-rune-vanishes-welcome-to-round-6-of-best-runes-souls-v0-h5se3i1qi93a1.png?width=640&crop=smart&auto=webp&s=1fe952380414f6b95fb43a4eddcdc0a92fb1ed4b)
Blank Rune vanishes! Welcome to ROUND 6 of Best Runes&Souls Poll game! (Poll in comments) : r/bindingofisaac
![According to Ed's recent Q&A, Blank Card will not work with Runes anymore in Repentance : r/bindingofisaac According to Ed's recent Q&A, Blank Card will not work with Runes anymore in Repentance : r/bindingofisaac](https://preview.redd.it/qb3nzpxfcfx41.jpg?width=640&crop=smart&auto=webp&s=2fb8b8dcdaff82a4999aa68d203391d766bf73f8)